Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Recruitment of SYK to the Activated BCR
Synonyms
Definitions

Edited: May, B, 2010-10-31 Reviewed: Wienands, J, 2012-02-11 Authored: May, B, 2010-10-31 The SYK protein tyrosine kinase binds specifically to phosphorylated immunoreceptor tyrosine-activated motifs (ITAMs) on Ig-alpha (CD79A, MB-1) and Ig-beta (CD79B, B29) (Law et al. 1994, Saouaf et al. 1995, Rowley et al. 1995, Tsang et al. 2008). The binding activates the kinase activity of SYK (Rowley et al. 1995, Tsang et al. 2008).

ID

http://purl.obolibrary.org/obo/HINO_0017754

comment

Edited: May, B, 2010-10-31

Reviewed: Wienands, J, 2012-02-11

Authored: May, B, 2010-10-31

The SYK protein tyrosine kinase binds specifically to phosphorylated immunoreceptor tyrosine-activated motifs (ITAMs) on Ig-alpha (CD79A, MB-1) and Ig-beta (CD79B, B29) (Law et al. 1994, Saouaf et al. 1995, Rowley et al. 1995, Tsang et al. 2008). The binding activates the kinase activity of SYK (Rowley et al. 1995, Tsang et al. 2008).

definition source

Reactome, http://www.reactome.org

Pubmed8163536

Pubmed18818202

Pubmed7592958

Pubmed7538118

has input

http://purl.obolibrary.org/obo/UniProt_P43405

http://purl.obolibrary.org/obo/HINO_0009220

has output

http://purl.obolibrary.org/obo/HINO_0009209

label

Recruitment of SYK to the Activated BCR

name

Recruitment of SYK to the Activated B Cell Receptor

prefixIRI

HINO:0017754

prefLabel

Recruitment of SYK to the Activated BCR

seeAlso

ReactomeREACT_118749

Reactome Database ID Release 43983700

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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