loading...| Preferred Name | CARMA1:BCL10:MALT1 Complex Recruits TAK1 and IKK | |
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Authored: May, B, 2010-12-18 TAK1 and the IKK complex are observed to migrate from the cytosol to lipid rafts containing the CARMA1:BCL10:MALT1 (CBM) complex (Sommer et al. 2005, Shinohara et al. 2005 using chicken cells). By analogy with activation of NF-KappaB signaling in T cells, TAK1 in B cells may also be bound to TAB1 and TAB2 or TAB3, which bind K63-conjugated polyubiquitin on a TRAF protein bound to the CBM complex (reviewed in Shinohara et al. 2009). Edited: May, B, 2010-12-18 Reviewed: Wienands, J, 2012-02-11 |
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http://purl.obolibrary.org/obo/HINO_0017742 |
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Authored: May, B, 2010-12-18 TAK1 and the IKK complex are observed to migrate from the cytosol to lipid rafts containing the CARMA1:BCL10:MALT1 (CBM) complex (Sommer et al. 2005, Shinohara et al. 2005 using chicken cells). By analogy with activation of NF-KappaB signaling in T cells, TAK1 in B cells may also be bound to TAB1 and TAB2 or TAB3, which bind K63-conjugated polyubiquitin on a TRAF protein bound to the CBM complex (reviewed in Shinohara et al. 2009). Edited: May, B, 2010-12-18 Reviewed: Wienands, J, 2012-02-11 |
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| definition source |
Pubmed16301747 Reactome, http://www.reactome.org Pubmed19909372 Pubmed16356855 |
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http://purl.obolibrary.org/obo/HINO_0009714 |
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CARMA1:BCL10:MALT1 Complex Recruits TAK1 and IKK |
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HINO:0017742 |
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CARMA1:BCL10:MALT1 Complex Recruits TAK1 and IKK |
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ReactomeREACT_118585 Reactome Database ID Release 431168637 |
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