Preferred Name | BLNK (SLP-65) Signalosome Generates Diacylglycerol and Inositol-1,4,5-trisphosphate | |
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Edited: May, B, 2011-01-19 Phospholipase C gamma (PLC-gamma) is activated by phosphorylation in response to antigen-binding by the B cell receptor (Carter et al. 1991, Roitman and Wang 1992, Rodriguez et al. 2001, Kim et al. 2004, Sekiya et al. 2004). Phospholipase C gamma hydrolyzes phosphatidylinositol-4,5-bisphosphate to yield inositol-1,4,5-trisphosphate and diacylglycerol (Carter et al. 1991, Kim et al. 2004). Human B cells contain both PLC-gamma1 and PLC-gamma2, with PLC-gamma2 predominating (Coggeshall et al. 1992). Authored: May, B, 2011-01-19 Reviewed: Wienands, J, 2012-02-11 |
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http://purl.obolibrary.org/obo/HINO_0017739 |
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comment |
Edited: May, B, 2011-01-19 Phospholipase C gamma (PLC-gamma) is activated by phosphorylation in response to antigen-binding by the B cell receptor (Carter et al. 1991, Roitman and Wang 1992, Rodriguez et al. 2001, Kim et al. 2004, Sekiya et al. 2004). Phospholipase C gamma hydrolyzes phosphatidylinositol-4,5-bisphosphate to yield inositol-1,4,5-trisphosphate and diacylglycerol (Carter et al. 1991, Kim et al. 2004). Human B cells contain both PLC-gamma1 and PLC-gamma2, with PLC-gamma2 predominating (Coggeshall et al. 1992). Authored: May, B, 2011-01-19 Reviewed: Wienands, J, 2012-02-11 |
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definition source |
Pubmed12181444 Pubmed1374290 Reactome, http://www.reactome.org Pubmed1599430 Pubmed3500860 Pubmed1376928 Pubmed2011584 Pubmed1705565 |
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label |
BLNK (SLP-65) Signalosome Generates Diacylglycerol and Inositol-1,4,5-trisphosphate |
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prefixIRI |
HINO:0017739 |
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prefLabel |
BLNK (SLP-65) Signalosome Generates Diacylglycerol and Inositol-1,4,5-trisphosphate |
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seeAlso |
Reactome Database ID Release 431112666 ReactomeREACT_118781 |
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subClassOf |