Human Interaction Network Ontology

Last uploaded: June 27, 2014
Jump to:
Id http://purl.obolibrary.org/obo/HINO_0017738
http://purl.obolibrary.org/obo/HINO_0017738
Preferred Name

Oligomerization of STIM1
Definitions
has a Stoichiometric coefficient of 2 Edited: May, B, 2011-01-19 Authored: May, B, 2011-01-19 Reviewed: Wienands, J, 2012-02-11 In the resting state the luminal domain of STIM1 binds Ca2+ ions within the endoplasmic reticulum and this binding prevents dimerization of STIM1 (Luik et al. 2008). Upon depletion of Ca2+ ions from the endoplasmic reticulum, STIM1 is no longer bound to Ca2+ and forms homodimers (Muik et al. 2008, Luik et al. 2008, Park et al. 2009).
Type http://www.w3.org/2002/07/owl#Class

All Properties

label
Oligomerization of STIM1
comment
has a Stoichiometric coefficient of 2
Edited: May, B, 2011-01-19
Authored: May, B, 2011-01-19
Reviewed: Wienands, J, 2012-02-11
In the resting state the luminal domain of STIM1 binds Ca2+ ions within the endoplasmic reticulum and this binding prevents dimerization of STIM1 (Luik et al. 2008). Upon depletion of Ca2+ ions from the endoplasmic reticulum, STIM1 is no longer bound to Ca2+ and forms homodimers (Muik et al. 2008, Luik et al. 2008, Park et al. 2009).
prefLabel
Oligomerization of STIM1
definition source
Pubmed18187424
Reactome, http://www.reactome.org
Pubmed19249086
Pubmed18596693
prefixIRI
HINO:0017738
seeAlso
ReactomeREACT_118808
Reactome Database ID Release 431168376
subClassOf
type
has input
has output
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display