loading...| Preferred Name | STIM1 Binds TRPC1 | |
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Edited: May, B, 2012-01-31 Authored: May, B, 2012-01-31 The polybasic region of STIM1 interacts with 2 aspartate residues in the C-terminal region of TRPC1 (Zeng et al. 2008, Huang et al. 2006). The STIM1:TRPC1 complex can form a tenary complex with ORAI1 (Ong et al. 2007, Jardin et al. 2008) and ORAI participates in function of STIM1:TRPC1 channels (Cheng et al. 2008, Cheng et al. 2011). As inferred from chicken DT40 cells, TRPC1 (and possibly other TRP channels) participates in store-operated calcium influx during signaling by the B cell receptor (Mori et al. 2002). Reviewed: Wienands, J, 2012-02-11 |
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http://purl.obolibrary.org/obo/HINO_0017737 |
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| comment |
Edited: May, B, 2012-01-31 Authored: May, B, 2012-01-31 The polybasic region of STIM1 interacts with 2 aspartate residues in the C-terminal region of TRPC1 (Zeng et al. 2008, Huang et al. 2006). The STIM1:TRPC1 complex can form a tenary complex with ORAI1 (Ong et al. 2007, Jardin et al. 2008) and ORAI participates in function of STIM1:TRPC1 channels (Cheng et al. 2008, Cheng et al. 2011). As inferred from chicken DT40 cells, TRPC1 (and possibly other TRP channels) participates in store-operated calcium influx during signaling by the B cell receptor (Mori et al. 2002). Reviewed: Wienands, J, 2012-02-11 |
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| definition source |
Pubmed21408196 Pubmed18995841 Pubmed18326500 Pubmed18420269 Pubmed22210847 Pubmed18843204 Pubmed11901194 Reactome, http://www.reactome.org Pubmed17486119 Pubmed17224452 Pubmed16906149 |
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STIM1 Binds TRPC1 |
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Formation of STIM1:TRPC1 Complex |
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| prefixIRI |
HINO:0017737 |
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STIM1 Binds TRPC1 |
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Reactome Database ID Release 432089927 ReactomeREACT_118759 |
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