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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Id | http://purl.obolibrary.org/obo/HINO_0016754
http://purl.obolibrary.org/obo/HINO_0016754
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| Preferred Name | Formation of tubulin folding intermediates by CCT/TriC |
| Definitions |
TriC/CCT forms a binary complex with unfolded alpha- or beta-tubulin (Frydman et al., 1992; Gao et al., 1993). The tubulin folding intermediates produced by TriC are unstable (Gao et al., 1993). Five additional protein cofactors (cofactor A-E) are required for the generation of properly folded alpha- and beta-tubulin and for the formation of alpha/beta-tubulin heterodimers (Gao et al., 1993) (Tian et al., 1997, Cowan and Lewis 2001).
Reviewed: Cowan, NJ, 2009-01-21 16:47:24
Edited: Matthews, L, 2009-02-21 04:38:35
Authored: Matthews, L, 2008-12-01 04:46:41
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Formation of tubulin folding intermediates by CCT/TriC
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| comment |
TriC/CCT forms a binary complex with unfolded alpha- or beta-tubulin (Frydman et al., 1992; Gao et al., 1993). The tubulin folding intermediates produced by TriC are unstable (Gao et al., 1993). Five additional protein cofactors (cofactor A-E) are required for the generation of properly folded alpha- and beta-tubulin and for the formation of alpha/beta-tubulin heterodimers (Gao et al., 1993) (Tian et al., 1997, Cowan and Lewis 2001).
Reviewed: Cowan, NJ, 2009-01-21 16:47:24
Edited: Matthews, L, 2009-02-21 04:38:35
Authored: Matthews, L, 2008-12-01 04:46:41
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| prefLabel |
Formation of tubulin folding intermediates by CCT/TriC
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| located_in | |
| definition source |
Pubmed1361170
Pubmed8096061
Reactome, http://www.reactome.org
Pubmed11868281
Pubmed9265649
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| prefixIRI |
HINO:0016754
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| seeAlso |
Reactome Database ID Release 43389960
ReactomeREACT_16956
GENE ONTOLOGYGO:0006457
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| subClassOf | |
| type | |
| has_part |
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