loading...| Preferred Name |
Formation of tubulin folding intermediates by CCT/TriC |
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| Synonyms |
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| Definitions |
TriC/CCT forms a binary complex with unfolded alpha- or beta-tubulin (Frydman et al., 1992; Gao et al., 1993). The tubulin folding intermediates produced by TriC are unstable (Gao et al., 1993). Five additional protein cofactors (cofactor A-E) are required for the generation of properly folded alpha- and beta-tubulin and for the formation of alpha/beta-tubulin heterodimers (Gao et al., 1993) (Tian et al., 1997, Cowan and Lewis 2001). Reviewed: Cowan, NJ, 2009-01-21 16:47:24 Edited: Matthews, L, 2009-02-21 04:38:35 Authored: Matthews, L, 2008-12-01 04:46:41 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0016754 |
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| comment |
TriC/CCT forms a binary complex with unfolded alpha- or beta-tubulin (Frydman et al., 1992; Gao et al., 1993). The tubulin folding intermediates produced by TriC are unstable (Gao et al., 1993). Five additional protein cofactors (cofactor A-E) are required for the generation of properly folded alpha- and beta-tubulin and for the formation of alpha/beta-tubulin heterodimers (Gao et al., 1993) (Tian et al., 1997, Cowan and Lewis 2001). Reviewed: Cowan, NJ, 2009-01-21 16:47:24 Edited: Matthews, L, 2009-02-21 04:38:35 Authored: Matthews, L, 2008-12-01 04:46:41 |
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| definition source |
Pubmed1361170 Pubmed8096061 Reactome, http://www.reactome.org Pubmed11868281 Pubmed9265649 |
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| label |
Formation of tubulin folding intermediates by CCT/TriC |
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| prefixIRI |
HINO:0016754 |
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| prefLabel |
Formation of tubulin folding intermediates by CCT/TriC |
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| seeAlso |
Reactome Database ID Release 43389960 ReactomeREACT_16956 GENE ONTOLOGYGO:0006457 |
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