Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
Synonyms
Definitions

RNA elements rich in adenine and uracil residues (AU-rich elements) bind specific proteins which either target the RNA for degradation or, more rarely, stabilize the RNA. The activity of the AU-element binding proteins is regulated, usually by phosphorylation but also by subcellular localization. Reviewed: Wilusz, J, 2010-06-29 Authored: May, B, 2009-12-29 Edited: May, B, 2009-12-29

ID

http://purl.obolibrary.org/obo/HINO_0016717

comment

RNA elements rich in adenine and uracil residues (AU-rich elements) bind specific proteins which either target the RNA for degradation or, more rarely, stabilize the RNA. The activity of the AU-element binding proteins is regulated, usually by phosphorylation but also by subcellular localization.

Reviewed: Wilusz, J, 2010-06-29

Authored: May, B, 2009-12-29

Edited: May, B, 2009-12-29

definition source

Pubmed16391004

Reactome, http://www.reactome.org

Pubmed15460540

Pubmed12704645

Pubmed12440953

label

Regulation of mRNA Stability by Proteins that Bind AU-rich Elements

located_in

http://purl.obolibrary.org/obo/NCBITaxon_9606

prefixIRI

HINO:0016717

prefLabel

Regulation of mRNA Stability by Proteins that Bind AU-rich Elements

seeAlso

ReactomeREACT_24994

Reactome Database ID Release 43450531

subClassOf

http://purl.obolibrary.org/obo/INO_0000021

has_part

http://purl.obolibrary.org/obo/HINO_0016708

http://purl.obolibrary.org/obo/HINO_0016715

http://purl.obolibrary.org/obo/HINO_0016713

http://purl.obolibrary.org/obo/HINO_0016714

http://purl.obolibrary.org/obo/HINO_0016716

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