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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Id | http://purl.obolibrary.org/obo/HINO_0016628
http://purl.obolibrary.org/obo/HINO_0016628
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|---|---|
| Preferred Name | RNA Polymerase I Promoter Opening |
| Definitions |
The activity of the upstream binding factor (UBF-1) plays an important role in the regulation of rRNA synthesis. Studies reveal that phosphorylation of UBF-1 is required for its interaction with the RNA polymerase I complex, suggesting that phosphorylation of UBF-1 bound to the rDNA promoter during promoter opening modulates the assembly of the transcription initiation complex.
Authored: Comai, L, 2003-07-03 17:13:29
Edited: Gillespie, ME, 0000-00-00 00:00:00
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
RNA Polymerase I Promoter Opening
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|---|---|
| comment |
The activity of the upstream binding factor (UBF-1) plays an important role in the regulation of rRNA synthesis. Studies reveal that phosphorylation of UBF-1 is required for its interaction with the RNA polymerase I complex, suggesting that phosphorylation of UBF-1 bound to the rDNA promoter during promoter opening modulates the assembly of the transcription initiation complex.
Authored: Comai, L, 2003-07-03 17:13:29
Edited: Gillespie, ME, 0000-00-00 00:00:00
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| prefLabel |
RNA Polymerase I Promoter Opening
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| located_in | |
| definition source |
Reactome, http://www.reactome.org
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| prefixIRI |
HINO:0016628
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| seeAlso |
GENE ONTOLOGYGO:0006361
Reactome Database ID Release 4373728
ReactomeREACT_2232
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| subClassOf | |
| type | |
| has_part |
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