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Human Interaction Network Ontology
| Preferred Name | Association of mTERF with the termination sequence | |
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| Definitions |
The 39-kDa mitochondrial transcription termination factor (mTERF), binds to a 28-base pair region of mtDNA (3237-3249) located within the tRNALeu(UUR) gene, at a position immediately downstream of the rRNA 16S gene (Fernandez-Silva et al., 1997; Kruse et al., 1989; Daga et al., 1993). mTERF binding to the termination sequence block transcription bidirectionally in a partially purified human mitochondrial system (Shang and Clayton, 1994). A polar termination activity has been also observed for the sea urchin homologue of mTERF, referred to as mtDBP with respect of phage RNA polymerases (Fernandez Silva et al. 2001). Reviewed: Cantatore, P, 0000-00-00 00:00:00 Edited: Matthews, L, 0000-00-00 00:00:00 Authored: Gustafsson, C, 2005-04-25 22:00:00 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0015932 |
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| comment |
The 39-kDa mitochondrial transcription termination factor (mTERF), binds to a 28-base pair region of mtDNA (3237-3249) located within the tRNALeu(UUR) gene, at a position immediately downstream of the rRNA 16S gene (Fernandez-Silva et al., 1997; Kruse et al., 1989; Daga et al., 1993). mTERF binding to the termination sequence block transcription bidirectionally in a partially purified human mitochondrial system (Shang and Clayton, 1994). A polar termination activity has been also observed for the sea urchin homologue of mTERF, referred to as mtDBP with respect of phage RNA polymerases (Fernandez Silva et al. 2001). Reviewed: Cantatore, P, 0000-00-00 00:00:00 Edited: Matthews, L, 0000-00-00 00:00:00 Authored: Gustafsson, C, 2005-04-25 22:00:00
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| definition source |
Pubmed11713324 Pubmed7525579 Reactome, http://www.reactome.org Pubmed7681833 Pubmed2752429 Pubmed9118945
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| label |
Association of mTERF with the termination sequence
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| prefixIRI |
HINO:0015932
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| prefLabel |
Association of mTERF with the termination sequence
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| seeAlso |
Reactome Database ID Release 43163320 ReactomeREACT_2027
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