Human Interaction Network Ontology

Last uploaded: June 27, 2014
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Id http://purl.obolibrary.org/obo/HINO_0015930
http://purl.obolibrary.org/obo/HINO_0015930
Preferred Name

TFAM binds to mitochondrial promoters
Definitions
Reviewed: Cantatore, P, 0000-00-00 00:00:00 Studies of human LSP have revealed that a minimal DNA fragment corresponding to position -28 to +16 relative to the transcription initiation site is able to support transcription initiation in a mitochondrial extract (Chang and Clayton, 1984). TFAM interacts directly with nucleotides between positions -35 and -17 (Fisher et al., 1987), and the exact distance between the TFAM-binding site and the transcription start site is essential for promoter activity (Dairaghi et al., 1995). Edited: Matthews, L, 0000-00-00 00:00:00 Authored: Gustafsson, C, 2005-04-25 22:00:00
Type http://www.w3.org/2002/07/owl#Class

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label
TFAM binds to mitochondrial promoters
comment
Reviewed: Cantatore, P, 0000-00-00 00:00:00
Studies of human LSP have revealed that a minimal DNA fragment corresponding to position -28 to +16 relative to the transcription initiation site is able to support transcription initiation in a mitochondrial extract (Chang and Clayton, 1984). TFAM interacts directly with nucleotides between positions -35 and -17 (Fisher et al., 1987), and the exact distance between the TFAM-binding site and the transcription start site is essential for promoter activity (Dairaghi et al., 1995).
Edited: Matthews, L, 0000-00-00 00:00:00
Authored: Gustafsson, C, 2005-04-25 22:00:00
prefLabel
TFAM binds to mitochondrial promoters
definition source
Pubmed6697390
Reactome, http://www.reactome.org
Pubmed7599198
Pubmed3594571
prefixIRI
HINO:0015930
seeAlso
Reactome Database ID Release 43163310
ReactomeREACT_875
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