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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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Id | http://purl.obolibrary.org/obo/HINO_0015794
http://purl.obolibrary.org/obo/HINO_0015794
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Preferred Name | RNA Polymerase III Promoter Opening at Type 1 Promoters |
Definitions |
Authored: Geiduschek, E, 2004-03-29 17:50:49
Pol III initiation complexes open the promoter spontaneously. Indeed, this is the general case for DNA-dependent RNA polymerases. Only pol II, with its requirement for TFIIH-directed and ATP-dependent promoter opening is exceptional. TFIIH introduces a layer of mechanism that is not in the repertoire of any other transcriptase. Thus, it is pol III-mediated transcription that is, from a mechanistic perspective, most directly comparable with archaeal and also bacterial transcription. <p>As promoter opening has been analyzed only in the S. cerevisiae this event is Inferred from the homologous pathway in yeast.
Edited: Gillespie, ME, 0000-00-00 00:00:00
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
label |
RNA Polymerase III Promoter Opening at Type 1 Promoters
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comment |
Authored: Geiduschek, E, 2004-03-29 17:50:49
Pol III initiation complexes open the promoter spontaneously. Indeed, this is the general case for DNA-dependent RNA polymerases. Only pol II, with its requirement for TFIIH-directed and ATP-dependent promoter opening is exceptional. TFIIH introduces a layer of mechanism that is not in the repertoire of any other transcriptase. Thus, it is pol III-mediated transcription that is, from a mechanistic perspective, most directly comparable with archaeal and also bacterial transcription. <p>As promoter opening has been analyzed only in the S. cerevisiae this event is Inferred from the homologous pathway in yeast.
Edited: Gillespie, ME, 0000-00-00 00:00:00
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prefLabel |
RNA Polymerase III Promoter Opening at Type 1 Promoters
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definition source |
Reactome, http://www.reactome.org
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prefixIRI |
HINO:0015794
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seeAlso |
GENE ONTOLOGYGO:0006383
ReactomeREACT_796
Reactome Database ID Release 4376060
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subClassOf | |
type | |
has input | |
has output |
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