Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

RNA Polymerase III Promoter Opening at Type 3 Promoters
Synonyms
Definitions

Authored: Geiduschek, E, 2004-03-29 17:50:49 Pol III initiation complexes open the promoter spontaneously. Indeed, this is the general case for DNA-dependent RNA polymerases. Only pol II, with its requirement for TFIIH-directed and ATP-dependent promoter opening is exceptional. TFIIH introduces a layer of mechanism that is not in the repertoire of any other transcriptase. Thus, it is pol III-mediated transcription that is, from a mechanistic perspective, most directly comparable with archaeal and also bacterial transcription. <p>As promoter opening has been analyzed only in the S. cerevisiae this event is Inferred from the homologous pathway in yeast. Edited: Gillespie, ME, 0000-00-00 00:00:00

ID

http://purl.obolibrary.org/obo/HINO_0015791

comment

Authored: Geiduschek, E, 2004-03-29 17:50:49

Pol III initiation complexes open the promoter spontaneously. Indeed, this is the general case for DNA-dependent RNA polymerases. Only pol II, with its requirement for TFIIH-directed and ATP-dependent promoter opening is exceptional. TFIIH introduces a layer of mechanism that is not in the repertoire of any other transcriptase. Thus, it is pol III-mediated transcription that is, from a mechanistic perspective, most directly comparable with archaeal and also bacterial transcription.

As promoter opening has been analyzed only in the S. cerevisiae this event is Inferred from the homologous pathway in yeast.

Edited: Gillespie, ME, 0000-00-00 00:00:00

definition source

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/HINO_0012651

has output

http://purl.obolibrary.org/obo/HINO_0012613

label

RNA Polymerase III Promoter Opening at Type 3 Promoters

prefixIRI

HINO:0015791

prefLabel

RNA Polymerase III Promoter Opening at Type 3 Promoters

seeAlso

Reactome Database ID Release 43112152

ReactomeREACT_1485

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

Delete Subject Author Type Created
No notes to display
Create mapping

Delete Mapping To Ontology Source
There are currently no mappings for this class.