Preferred Name | Phosphorylation of BRF1 by MK2 | |
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Definitions |
MAPK-activated protein kinase 2 (MK2) phosphorylates BRF1 at serine 54, serine 92, serine 203, and an unknown site in the C terminus. Phosphorylation inhibits the ability of BRF1 to cause degradation of RNA. It is unknown if tetraphosphorylated BRF1 binds 14-3-3 in the same way as diphosphorylated BRF1 does. has a Stoichiometric coefficient of 3 Reviewed: Wilusz, J, 2010-06-29 Authored: May, B, 2009-12-29 Edited: May, B, 2009-12-29 |
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ID |
http://purl.obolibrary.org/obo/HINO_0015639 |
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comment |
MAPK-activated protein kinase 2 (MK2) phosphorylates BRF1 at serine 54, serine 92, serine 203, and an unknown site in the C terminus. Phosphorylation inhibits the ability of BRF1 to cause degradation of RNA. It is unknown if tetraphosphorylated BRF1 binds 14-3-3 in the same way as diphosphorylated BRF1 does. has a Stoichiometric coefficient of 3 Reviewed: Wilusz, J, 2010-06-29 Authored: May, B, 2009-12-29 Edited: May, B, 2009-12-29 |
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definition source |
Pubmed18326031 Reactome, http://www.reactome.org |
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label |
Phosphorylation of BRF1 by MK2 |
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prefixIRI |
HINO:0015639 |
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prefLabel |
Phosphorylation of BRF1 by MK2 |
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seeAlso |
Reactome Database ID Release 43450474 ReactomeREACT_25285 EC Number: 2.7.11 |
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subClassOf |