loading...| Preferred Name | BRF1 Complex Recruits RNA Degradation Activities | |
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Reviewed: Wilusz, J, 2010-06-29 Authored: May, B, 2009-12-29 Edited: May, B, 2009-12-29 BRF1 recruits RNA degradation activities to hydrolyze the RNA bound to BRF1. Coimmunoprecipitation has shown BRF1 interacts with the exosome (3' to 5' nuclease), XRN1 (5' to 3' nuclease), and DCP1a and DCP2 (decapping). BRF1 localizes RNAs to processing bodies, sites of translation repression and possible sites of RNA degradation. |
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http://purl.obolibrary.org/obo/HINO_0015637 |
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Reviewed: Wilusz, J, 2010-06-29 Authored: May, B, 2009-12-29 Edited: May, B, 2009-12-29 BRF1 recruits RNA degradation activities to hydrolyze the RNA bound to BRF1. Coimmunoprecipitation has shown BRF1 interacts with the exosome (3' to 5' nuclease), XRN1 (5' to 3' nuclease), and DCP1a and DCP2 (decapping). BRF1 localizes RNAs to processing bodies, sites of translation repression and possible sites of RNA degradation. |
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Pubmed11719186 Pubmed14976220 Reactome, http://www.reactome.org Pubmed17369404 Pubmed15687258 |
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http://purl.obolibrary.org/obo/UniProt_Q8IU60 http://purl.obolibrary.org/obo/UniProt_Q9NPI6 http://purl.obolibrary.org/obo/UniProt_Q8IZH2 |
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BRF1 Complex Recruits RNA Degradation Activities |
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HINO:0015637 |
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BRF1 Complex Recruits RNA Degradation Activities |
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Reactome Database ID Release 43450488 ReactomeREACT_25265 |
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