Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

KSRP Recruits RNA Degradation Activities
Synonyms
Definitions

KSRP (KHSRP) forms a complex with the PARN deadenylase, exosome components (3' to 5' mRNA decay), and the decapping enzyme DCP2. Tethering KSRP to a mRNA is sufficient to target the mRNA for degradation. Reviewed: Wilusz, J, 2010-06-29 Authored: May, B, 2009-12-29 Edited: May, B, 2009-12-29

ID

http://purl.obolibrary.org/obo/HINO_0015614

comment

KSRP (KHSRP) forms a complex with the PARN deadenylase, exosome components (3' to 5' mRNA decay), and the decapping enzyme DCP2. Tethering KSRP to a mRNA is sufficient to target the mRNA for degradation.

Reviewed: Wilusz, J, 2010-06-29

Authored: May, B, 2009-12-29

Edited: May, B, 2009-12-29

definition source

Pubmed11719186

Reactome, http://www.reactome.org

Pubmed16648466

Pubmed15175153

has input

http://purl.obolibrary.org/obo/UniProt_Q8IU60

http://purl.obolibrary.org/obo/UniProt_O95453

http://purl.obolibrary.org/obo/HINO_0013331

http://purl.obolibrary.org/obo/HINO_0012782

has output

http://purl.obolibrary.org/obo/HINO_0013300

label

KSRP Recruits RNA Degradation Activities

prefixIRI

HINO:0015614

prefLabel

KSRP Recruits RNA Degradation Activities

seeAlso

Reactome Database ID Release 43450422

ReactomeREACT_25257

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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