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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Preferred Name | Phosphorylated KSRP (Ser193) Binds 14-3-3zeta in the Nucleus | |
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| Definitions |
KSRP phosphorylated at serine193 binds 14-3-3zeta which impairs the ability of KSRP to destabilize RNA. Thus the RNAs become stabilized. KSRP is able to shuttle between the nucleus and the cytoplasm. 14-3-3zeta is nucleoplasmic. Binding of KSRP to 14-3-3zeta causes KSRP to be retained in the nucleus. Reviewed: Wilusz, J, 2010-06-29 Authored: May, B, 2009-12-29 Edited: May, B, 2009-12-29 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0015612 |
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| comment |
KSRP phosphorylated at serine193 binds 14-3-3zeta which impairs the ability of KSRP to destabilize RNA. Thus the RNAs become stabilized. KSRP is able to shuttle between the nucleus and the cytoplasm. 14-3-3zeta is nucleoplasmic. Binding of KSRP to 14-3-3zeta causes KSRP to be retained in the nucleus. Reviewed: Wilusz, J, 2010-06-29 Authored: May, B, 2009-12-29 Edited: May, B, 2009-12-29
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| definition source |
Pubmed19198587 Reactome, http://www.reactome.org
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| label |
Phosphorylated KSRP (Ser193) Binds 14-3-3zeta in the Nucleus
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| prefixIRI |
HINO:0015612
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| prefLabel |
Phosphorylated KSRP (Ser193) Binds 14-3-3zeta in the Nucleus
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| seeAlso |
Reactome Database ID Release 43450620 ReactomeREACT_25152
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