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Human Interaction Network Ontology
| Preferred Name | snRNP Assembly | |
| Synonyms |
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| Definitions |
Reviewed: Luhrmann, R, 2007-04-30 18:31:22 Authored: Gillespie, ME, 2007-01-29 20:29:54 Small nuclear ribonucleoproteins (snRNPs) are crucial for pre-mRNA processing to mRNAs. Each snRNP contains a small nuclear RNA (snRNA) and an extremely stable core of seven Sm proteins. The U6 snRNA differs from the other snRNAs; it binds seven Sm-like proteins and its assembly does not involve a cytoplasmic phase. The snRNP biogenesis pathway for all of the other snRNAs is complex, involving nuclear export of snRNA, Sm-core assembly in the cytoplasm and re-import of the mature snRNP. The assembly of the snRNA:Sm-core is carried out by the survival of motor neurons (SMN) complex. The SMN complex stringently scrutinizes RNAs for specific features that define them as snRNAs and binds the RNA-binding Sm proteins. |
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| ID |
http://purl.obolibrary.org/obo/HINO_0015390 |
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| comment |
Reviewed: Luhrmann, R, 2007-04-30 18:31:22 Authored: Gillespie, ME, 2007-01-29 20:29:54 Small nuclear ribonucleoproteins (snRNPs) are crucial for pre-mRNA processing to mRNAs. Each snRNP contains a small nuclear RNA (snRNA) and an extremely stable core of seven Sm proteins. The U6 snRNA differs from the other snRNAs; it binds seven Sm-like proteins and its assembly does not involve a cytoplasmic phase. The snRNP biogenesis pathway for all of the other snRNAs is complex, involving nuclear export of snRNA, Sm-core assembly in the cytoplasm and re-import of the mature snRNP. The assembly of the snRNA:Sm-core is carried out by the survival of motor neurons (SMN) complex. The SMN complex stringently scrutinizes RNAs for specific features that define them as snRNAs and binds the RNA-binding Sm proteins.
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| definition source |
Reactome, http://www.reactome.org Pubmed15130578
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| label |
snRNP Assembly
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| located_in | ||
| prefixIRI |
HINO:0015390
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| prefLabel |
snRNP Assembly
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| seeAlso |
Reactome Database ID Release 43191859 ReactomeREACT_11066 GENE ONTOLOGYGO:0000387
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| subClassOf | ||
| has_part |
http://purl.obolibrary.org/obo/HINO_0014848 http://purl.obolibrary.org/obo/HINO_0014842 http://purl.obolibrary.org/obo/HINO_0014841 http://purl.obolibrary.org/obo/HINO_0014847 |
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