loading...| Preferred Name | Partial Deadenylation of mRNA by the PAN2-PAN3 Complex | |
| Synonyms |
|
|
| Definitions |
Edited: May, B, 2009-07-22 Reviewed: Wilusz, J, 2009-09-17 Authored: May, B, 2009-07-22 The PAN2-PAN3 exoribonuclease complex hydrolyzes the poly(A) tail of a mRNA, shortening the tail from about 200 adenosine residues to about 80 adenosine residues and yielding adenosine 5'-monophosphate. PAN2 is the exoribonuclease component of the complex; PAN3 is required for cellular localization. The poly(A)-binding protein (PABP) interacts with PAN3 and recruits the PAN2-PAN3 complex to mRNA. |
|
| ID |
http://purl.obolibrary.org/obo/HINO_0015255 |
|
| comment |
Edited: May, B, 2009-07-22 Reviewed: Wilusz, J, 2009-09-17 Authored: May, B, 2009-07-22 The PAN2-PAN3 exoribonuclease complex hydrolyzes the poly(A) tail of a mRNA, shortening the tail from about 200 adenosine residues to about 80 adenosine residues and yielding adenosine 5'-monophosphate. PAN2 is the exoribonuclease component of the complex; PAN3 is required for cellular localization. The poly(A)-binding protein (PABP) interacts with PAN3 and recruits the PAN2-PAN3 complex to mRNA. |
|
| definition source |
Pubmed11283721 Pubmed15475613 Pubmed16141059 Reactome, http://www.reactome.org Pubmed14583602 Pubmed17595167 Pubmed16284618 Pubmed14749774 Pubmed17245413 Pubmed19239894 Pubmed18625844 |
|
| has input | ||
| has output | ||
| label |
Partial Deadenylation of mRNA by the PAN2-PAN3 Complex |
|
| prefixIRI |
HINO:0015255 |
|
| prefLabel |
Partial Deadenylation of mRNA by the PAN2-PAN3 Complex |
|
| seeAlso |
ReactomeREACT_20606 EC Number: 3.1.13.4 Reactome Database ID Release 43430021 |
|
| subClassOf |