Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Transesterification to connect viral DNA 3' ends to host DNA 5' ends
Synonyms
Definitions

The first chemical step of integration involves a single step transesterification, in which the recessed 3' hydroxyl of the viral DNA becomes covalently joined to a protruding 5' end in the target DNA. This step at the same time cleaves the target DNA. Reviewed: Bushman, FD, 2006-10-30 22:19:13 Edited: Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22 Authored: Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22

ID

http://purl.obolibrary.org/obo/HINO_0015148

comment

The first chemical step of integration involves a single step transesterification, in which the recessed 3' hydroxyl of the viral DNA becomes covalently joined to a protruding 5' end in the target DNA. This step at the same time cleaves the target DNA.

Reviewed: Bushman, FD, 2006-10-30 22:19:13

Edited: Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22

Authored: Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22

definition source

Pubmed1329090

Pubmed7956067

Pubmed8883604

Pubmed15308744

Reactome, http://www.reactome.org

Pubmed1317268

Pubmed12407101

Pubmed1310932

Pubmed9557688

Pubmed15677323

Pubmed16260736

has input

http://purl.obolibrary.org/obo/HINO_0013813

http://purl.obolibrary.org/obo/HINO_0013866

has output

http://purl.obolibrary.org/obo/HINO_0013867

http://purl.obolibrary.org/obo/HINO_0013866

label

Transesterification to connect viral DNA 3' ends to host DNA 5' ends

prefixIRI

HINO:0015148

prefLabel

Transesterification to connect viral DNA 3' ends to host DNA 5' ends

seeAlso

Reactome Database ID Release 43164523

ReactomeREACT_9048

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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