Human Interaction Network Ontology

Last uploaded: June 27, 2014
Jump to:
Id http://purl.obolibrary.org/obo/HINO_0014833
http://purl.obolibrary.org/obo/HINO_0014833
Preferred Name

Peptide transfer from P-site tRNA to the A-site tRNA
Definitions
The A- and P-sites of the ribosome positions the aa-tRNA and peptidyl-tRNA such that a nucleophilic attack can occur between the amine group of the A-site aa-tRNA and the carbonyl group of the growing peptide chain on the P-site tRNA, resulting in the formation of a peptide bond. The carboxyl end of the peptide chain is uncoupled from the tRNA molecule in the P-site and forms a new peptide bond with the amino acid that is in the A-site.<br>This process is illustrated below with: a peptidyl-tRNA with a growing peptide,a deacylated tRNA with an -OH and a ribosome with A,P and E sites to accommodate these three forms of tRNA.
Type http://www.w3.org/2002/07/owl#Class

All Properties

label
Peptide transfer from P-site tRNA to the A-site tRNA
comment
The A- and P-sites of the ribosome positions the aa-tRNA and peptidyl-tRNA such that a nucleophilic attack can occur between the amine group of the A-site aa-tRNA and the carbonyl group of the growing peptide chain on the P-site tRNA, resulting in the formation of a peptide bond. The carboxyl end of the peptide chain is uncoupled from the tRNA molecule in the P-site and forms a new peptide bond with the amino acid that is in the A-site.<br>This process is illustrated below with: a peptidyl-tRNA with a growing peptide,a deacylated tRNA with an -OH and a ribosome with A,P and E sites to accommodate these three forms of tRNA.
prefLabel
Peptide transfer from P-site tRNA to the A-site tRNA
definition source
Pubmed1620067
Reactome, http://www.reactome.org
Pubmed12297040
prefixIRI
HINO:0014833
seeAlso
EC Number: 2.3.2.12
Reactome Database ID Release 43156912
ReactomeREACT_1227
subClassOf
type
has input
has output
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display