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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Id | http://purl.obolibrary.org/obo/HINO_0014832
http://purl.obolibrary.org/obo/HINO_0014832
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|---|---|
| Preferred Name | Hydrolysis of eEF1A:GTP |
| Definitions |
Authored: Gopinathrao, G, 2005-03-17 13:24:01
Once the correct codon-anticodon match occurs between the mRNA and aa-tRNA, the decoding event triggers GTP hydrolysis on eEF1A. The resulting conformational change releases the aa-tRNA to the A-site, and GDP bound form of eEF1A is released from the ribosome.<br>This process is illustrated below with: an amino acyl-tRNA with an amino acid,a peptidyl-tRNA with a growing peptide and a ribosome with A,P and E sites to accommodate these two forms of tRNA.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Hydrolysis of eEF1A:GTP
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| comment |
Authored: Gopinathrao, G, 2005-03-17 13:24:01
Once the correct codon-anticodon match occurs between the mRNA and aa-tRNA, the decoding event triggers GTP hydrolysis on eEF1A. The resulting conformational change releases the aa-tRNA to the A-site, and GDP bound form of eEF1A is released from the ribosome.<br>This process is illustrated below with: an amino acyl-tRNA with an amino acid,a peptidyl-tRNA with a growing peptide and a ribosome with A,P and E sites to accommodate these two forms of tRNA.
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| prefLabel |
Hydrolysis of eEF1A:GTP
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| definition source |
Pubmed6568109
Reactome, http://www.reactome.org
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| prefixIRI |
HINO:0014832
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| seeAlso |
EC Number: 3.6.5.3
ReactomeREACT_552
EC Number: 3.6.5.2
EC Number: 3.6.5.1
EC Number: 3.6.5.4
Reactome Database ID Release 43156923
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