Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress
Synonyms
Definitions

Authored: Akkerman, JW, 2009-06-03 Edited: Jupe, S, 2010-06-07 Reviewed: Kunapuli, SP, 2010-06-07 High shear stress, or immobilization of VWF under high shear conditions induce VWF binding to GPIb-IX-V. This activation mechanism is believed to involve shear-stress induced conformational changes in vWF.

ID

http://purl.obolibrary.org/obo/HINO_0014382

comment

Authored: Akkerman, JW, 2009-06-03

Edited: Jupe, S, 2010-06-07

Reviewed: Kunapuli, SP, 2010-06-07

High shear stress, or immobilization of VWF under high shear conditions induce VWF binding to GPIb-IX-V. This activation mechanism is believed to involve shear-stress induced conformational changes in vWF.

definition source

Pubmed8631758

Pubmed10627461

Reactome, http://www.reactome.org

Pubmed2010539

has input

http://purl.obolibrary.org/obo/HINO_0005492

has output

http://purl.obolibrary.org/obo/HINO_0005490

http://purl.obolibrary.org/obo/HINO_0005491

label

GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress

prefixIRI

HINO:0014382

prefLabel

GPIb-IX-V binding to 14-3-3 zeta is reduced by shear stress

seeAlso

Reactome Database ID Release 43430073

ReactomeREACT_23970

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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