Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

CDCA5 (Sororin) enables cohesion of sister centromeres
Synonyms
Definitions

Reviewed: Zhang, Nenggang, 2012-10-22 Edited: Matthews, L, 2012-10-05 Authored: Orlic-Milacic, M, 2012-10-02 CDCA5 (Sororin) is essential for the establishment of sister chromatid cohesion at centromeres. Experiments in which a recombinant tagged mouse CDCA5 was expressed in human HeLa cell line showed that CDCA5 starts to accumulate on chromatin in S-phase and dissociates from centromeres in anaphase (Nishiyama et al. 2010). Edited: Gillespie, ME, 2012-10-05

ID

http://purl.obolibrary.org/obo/HINO_0011519

comment

Reviewed: Zhang, Nenggang, 2012-10-22

Edited: Matthews, L, 2012-10-05

Authored: Orlic-Milacic, M, 2012-10-02

CDCA5 (Sororin) is essential for the establishment of sister chromatid cohesion at centromeres. Experiments in which a recombinant tagged mouse CDCA5 was expressed in human HeLa cell line showed that CDCA5 starts to accumulate on chromatin in S-phase and dissociates from centromeres in anaphase (Nishiyama et al. 2010).

Edited: Gillespie, ME, 2012-10-05

definition source

Pubmed21111234

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/UniProt_Q96FF9

http://purl.obolibrary.org/obo/HINO_0022642

http://purl.obolibrary.org/obo/HINO_0004268

has output

http://purl.obolibrary.org/obo/HINO_0022646

label

CDCA5 (Sororin) enables cohesion of sister centromeres

prefixIRI

HINO:0011519

prefLabel

CDCA5 (Sororin) enables cohesion of sister centromeres

seeAlso

Reactome Database ID Release 432473151

ReactomeREACT_150445

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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