Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Dephosphorylation of p107 by PP2A
Synonyms
Definitions

Reviewed: Grana, X, 2011-06-15 Authored: Orlic-Milacic, Marija, 2011-06-14 has a Stoichiometric coefficient of 4 Dephosphorylation of p107 (RBL1) by PP2A complex containing either PPP2R3B (B" beta) or PPP2R2A (B alpha) regulatory subunit plays a role in maintaining the equilibrium of hyperphosphorylated and hypophosphorylated p107 (RBL1), through counteracting action of cyclin dependent kinases (CDKs) throughout the cell cycle. It is assumed that PP2A dephosphorylates p107 (RBL1) on all four phosphorylation sites, but further experiments are needed to confirm this.

ID

http://purl.obolibrary.org/obo/HINO_0011425

comment

Reviewed: Grana, X, 2011-06-15

Authored: Orlic-Milacic, Marija, 2011-06-14

has a Stoichiometric coefficient of 4

Dephosphorylation of p107 (RBL1) by PP2A complex containing either PPP2R3B (B" beta) or PPP2R2A (B alpha) regulatory subunit plays a role in maintaining the equilibrium of hyperphosphorylated and hypophosphorylated p107 (RBL1), through counteracting action of cyclin dependent kinases (CDKs) throughout the cell cycle. It is assumed that PP2A dephosphorylates p107 (RBL1) on all four phosphorylation sites, but further experiments are needed to confirm this.

definition source

Reactome, http://www.reactome.org

Pubmed20663872

has input

http://purl.obolibrary.org/obo/UniProt_P28749

http://purl.obolibrary.org/obo/CHEBI_15377

has output

http://purl.obolibrary.org/obo/UniProt_P28749

http://purl.obolibrary.org/obo/CHEBI_18367

label

Dephosphorylation of p107 by PP2A

name

Dephosphorylation of p107 (RBL1) by PP2A

prefixIRI

HINO:0011425

prefLabel

Dephosphorylation of p107 by PP2A

seeAlso

EC Number: 3.1.3.16

ReactomeREACT_111148

Reactome Database ID Release 431363274

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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