Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Formation of Cyclin D:Cdk4/6 complexes
Synonyms
Definitions

The formation of CyclinD:CDK4/6 complexes is promoted by two proteins, p21Cip1/Waf1 and p27kip1. Activity of the cyclin-dependent kinases 4 and 6 can be inhibited by the binding of several small CDK-inhibitory proteins (CKIs). Edited: Matthews, L, 2006-07-03 08:41:56

ID

http://purl.obolibrary.org/obo/HINO_0011351

comment

The formation of CyclinD:CDK4/6 complexes is promoted by two proteins, p21Cip1/Waf1 and p27kip1. Activity of the cyclin-dependent kinases 4 and 6 can be inhibited by the binding of several small CDK-inhibitory proteins (CKIs).

Edited: Matthews, L, 2006-07-03 08:41:56

definition source

Pubmed9106657

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/HINO_0010405

http://purl.obolibrary.org/obo/CHEBI_15422

http://purl.obolibrary.org/obo/HINO_0010412

http://purl.obolibrary.org/obo/HINO_0010415

has output

http://purl.obolibrary.org/obo/HINO_0024300

http://purl.obolibrary.org/obo/CHEBI_16761

label

Formation of Cyclin D:Cdk4/6 complexes

prefixIRI

HINO:0011351

prefLabel

Formation of Cyclin D:Cdk4/6 complexes

seeAlso

ReactomeREACT_2081

Reactome Database ID Release 4369213

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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