Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2
Synonyms
Definitions

p130 (RBL2) in complex with E2F4/5 and DP1/2 binds to cyclin A or cyclin E in complex with CDK2 through its conserved LFG pocket domain motif and amino terminus, leading to inhibition of CDK2 kinase activity and suppression of cellular growth. Authored: Orlic-Milacic, Marija, 2011-06-14 Reviewed: MacPherson, D, 2011-08-25

ID

http://purl.obolibrary.org/obo/HINO_0011350

comment

p130 (RBL2) in complex with E2F4/5 and DP1/2 binds to cyclin A or cyclin E in complex with CDK2 through its conserved LFG pocket domain motif and amino terminus, leading to inhibition of CDK2 kinase activity and suppression of cellular growth.

Authored: Orlic-Milacic, Marija, 2011-06-14

Reviewed: MacPherson, D, 2011-08-25

definition source

Reactome, http://www.reactome.org

Pubmed9199292

has input

http://purl.obolibrary.org/obo/HINO_0024322

http://purl.obolibrary.org/obo/HINO_0024293

has output

http://purl.obolibrary.org/obo/HINO_0024301

label

p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2

prefixIRI

HINO:0011350

prefLabel

p130 (RBL2) in complex with E2F4/5:DP1/2 binds to cyclin E/A:CDK2

seeAlso

Reactome Database ID Release 431363303

ReactomeREACT_111109

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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