loading...| Preferred Name | CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix | |
| Synonyms |
|
|
| Definitions |
has a Stoichiometric coefficient of 2 Edited: Orlic-Milacic, Marija, 2011-08-25 Reviewed: Heldin, CH, 2008-02-12 09:44:02 Beta-Pix (Cool-1) associates with CBL, which appears to be a critical step in CDC42-mediated inhibition of EGFR ubiquitylation and downregulation. The SH3 domain of Beta-Pix specifically interacts with a proline-arginine motif (PxxxPR) present within CBL, which mediates ubiquitylation and subsequent degradation of Beta-Pix. Authored: Castagnoli, L, 2006-10-10 13:09:34 |
|
| ID |
http://purl.obolibrary.org/obo/HINO_0009873 |
|
| comment |
has a Stoichiometric coefficient of 2 Edited: Orlic-Milacic, Marija, 2011-08-25 Reviewed: Heldin, CH, 2008-02-12 09:44:02 Beta-Pix (Cool-1) associates with CBL, which appears to be a critical step in CDC42-mediated inhibition of EGFR ubiquitylation and downregulation. The SH3 domain of Beta-Pix specifically interacts with a proline-arginine motif (PxxxPR) present within CBL, which mediates ubiquitylation and subsequent degradation of Beta-Pix. Authored: Castagnoli, L, 2006-10-10 13:09:34 |
|
| definition source |
Reactome, http://www.reactome.org Pubmed16407834 |
|
| has input | ||
| has output | ||
| label |
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix |
|
| prefixIRI |
HINO:0009873 |
|
| prefLabel |
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix |
|
| seeAlso |
ReactomeREACT_12451 EC Number: 6.3.2.19 Reactome Database ID Release 43183084 |
|
| subClassOf |