loading...| Preferred Name | CBL ubiquitinates Sprouty | |
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Edited: Orlic-Milacic, Marija, 2011-08-25 Reviewed: Heldin, CH, 2008-02-12 09:44:02 Sprouty is ubiquitinated by CBL in an EGF-dependent manner. EGF stimulation induces the tyrosine phosphorylation of Sprouty, which in turn enhances the interaction of Sprouty with CBL. The CBL-mediated ubiquitination of Sprouty targets the protein for degradation by the 26S proteasome. Authored: Castagnoli, L, 2006-10-10 13:09:34 |
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http://purl.obolibrary.org/obo/HINO_0009867 |
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Edited: Orlic-Milacic, Marija, 2011-08-25 Reviewed: Heldin, CH, 2008-02-12 09:44:02 Sprouty is ubiquitinated by CBL in an EGF-dependent manner. EGF stimulation induces the tyrosine phosphorylation of Sprouty, which in turn enhances the interaction of Sprouty with CBL. The CBL-mediated ubiquitination of Sprouty targets the protein for degradation by the 26S proteasome. Authored: Castagnoli, L, 2006-10-10 13:09:34 |
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| definition source |
Reactome, http://www.reactome.org Pubmed12593796 |
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CBL ubiquitinates Sprouty |
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HINO:0009867 |
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CBL ubiquitinates Sprouty |
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EC Number: 6.3.2.19 Reactome Database ID Release 43183051 ReactomeREACT_12381 |
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