Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Beta-Pix pushes CIN85 away from CBL
Synonyms
Definitions

has a Stoichiometric coefficient of 2 Edited: Orlic-Milacic, Marija, 2011-08-25 Reviewed: Heldin, CH, 2008-02-12 09:44:02 Authored: Castagnoli, L, 2006-10-10 13:09:34 High concentrations of active CDC42 and Beta-Pix may promote the binding of Beta-Pix to CBL, pushing out the usually preferred binding partner CIN85 from the CBL complex. This competitive mechanism could block the CIN85-imposed clustering phenomenon on CBL that is required for tighter binding.

ID

http://purl.obolibrary.org/obo/HINO_0009820

comment

has a Stoichiometric coefficient of 2

Edited: Orlic-Milacic, Marija, 2011-08-25

Reviewed: Heldin, CH, 2008-02-12 09:44:02

Authored: Castagnoli, L, 2006-10-10 13:09:34

High concentrations of active CDC42 and Beta-Pix may promote the binding of Beta-Pix to CBL, pushing out the usually preferred binding partner CIN85 from the CBL complex. This competitive mechanism could block the CIN85-imposed clustering phenomenon on CBL that is required for tighter binding.

definition source

Reactome, http://www.reactome.org

Pubmed16407834

has input

http://purl.obolibrary.org/obo/HINO_0012688

http://purl.obolibrary.org/obo/HINO_0012664

has output

http://purl.obolibrary.org/obo/UniProt_Q96B97

http://purl.obolibrary.org/obo/HINO_0012663

label

Beta-Pix pushes CIN85 away from CBL

prefixIRI

HINO:0009820

prefLabel

Beta-Pix pushes CIN85 away from CBL

seeAlso

Reactome Database ID Release 43183002

ReactomeREACT_12412

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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