Preferred Name | Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants | |
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Definitions |
has a Stoichiometric coefficient of 2 Edited: Wu, G, 2011-11-07 Authored: Orlic-Milacic, M, 2011-11-04 Edited: D'Eustachio, P, 2011-11-07 Edited: Gillespie, ME, 2011-11-07 Edited: Matthews, L, 2011-11-07 Reviewed: Greulich, H, 2011-11-15 Reviewed: Savas, S, 2011-11-15 EGFR L858R mutant was shown to directly phosphorylate CBL on tyrosine residue Y371. Other EGFR cancer mutants with phosphorylation of tyrosine Y1045 (Y1069) are assumed to bind and phosphorylate CBL in a manner similar to the wild-type EGFR. |
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ID |
http://purl.obolibrary.org/obo/HINO_0009781 |
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comment |
has a Stoichiometric coefficient of 2 Edited: Wu, G, 2011-11-07 Authored: Orlic-Milacic, M, 2011-11-04 Edited: D'Eustachio, P, 2011-11-07 Edited: Gillespie, ME, 2011-11-07 Edited: Matthews, L, 2011-11-07 Reviewed: Greulich, H, 2011-11-15 Reviewed: Savas, S, 2011-11-15 EGFR L858R mutant was shown to directly phosphorylate CBL on tyrosine residue Y371. Other EGFR cancer mutants with phosphorylation of tyrosine Y1045 (Y1069) are assumed to bind and phosphorylate CBL in a manner similar to the wild-type EGFR. |
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definition source |
Reactome, http://www.reactome.org Pubmed16849543 |
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label |
Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants |
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prefixIRI |
HINO:0009781 |
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prefLabel |
Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants |
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seeAlso |
ReactomeREACT_115796 EC Number: 2.7.10 Reactome Database ID Release 431225960 |
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subClassOf |