Preferred Name | Phosphorylated SHC1 in complex with p-EGFR mutants recruits GRB2:SOS1 complex | |
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Edited: Wu, G, 2011-11-07 Authored: Orlic-Milacic, M, 2011-11-04 Edited: D'Eustachio, P, 2011-11-07 Recruitment of GRB2:SOS1 complex by SHC1 bound to phosphorylated dimers of EGFR cancer mutants has not been directly tested, but is assumed to happen in the same way it happens with the SHC1 bound to the phosphorylated homodimer of wild-type EGFR. Edited: Matthews, L, 2011-11-07 Reviewed: Greulich, H, 2011-11-15 Reviewed: Savas, S, 2011-11-15 |
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http://purl.obolibrary.org/obo/HINO_0009761 |
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comment |
Edited: Wu, G, 2011-11-07 Authored: Orlic-Milacic, M, 2011-11-04 Edited: D'Eustachio, P, 2011-11-07 Recruitment of GRB2:SOS1 complex by SHC1 bound to phosphorylated dimers of EGFR cancer mutants has not been directly tested, but is assumed to happen in the same way it happens with the SHC1 bound to the phosphorylated homodimer of wild-type EGFR. Edited: Matthews, L, 2011-11-07 Reviewed: Greulich, H, 2011-11-15 Reviewed: Savas, S, 2011-11-15 |
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definition source |
Pubmed8493579 Reactome, http://www.reactome.org Pubmed15284455 |
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label |
Phosphorylated SHC1 in complex with p-EGFR mutants recruits GRB2:SOS1 complex |
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prefixIRI |
HINO:0009761 |
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prefLabel |
Phosphorylated SHC1 in complex with p-EGFR mutants recruits GRB2:SOS1 complex |
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seeAlso |
Reactome Database ID Release 431225961 ReactomeREACT_115562 |
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