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Human Interaction Network Ontology
Last uploaded:
June 27, 2014
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| Id | http://purl.obolibrary.org/obo/HINO_0009759
http://purl.obolibrary.org/obo/HINO_0009759
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| Preferred Name | Phosphorylation of SHC1 by p-EGFR mutants |
| Definitions |
has a Stoichiometric coefficient of 2
Edited: Wu, G, 2011-11-07
Authored: Orlic-Milacic, M, 2011-11-04
Edited: D'Eustachio, P, 2011-11-07
Edited: Matthews, L, 2011-11-07
Reviewed: Greulich, H, 2011-11-15
Reviewed: Savas, S, 2011-11-15
Constitutive phosphorylation of SHC1 was directly demonstrated in cells expressing EGFR L858R mutant (Greulich et al. 2005). Other EGFR cancer mutants were not directly tested for their ability to phosphorylate SHC1, but are assumed to interact with SHC1 in the same way as the wild-type EGFR protein.
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label |
Phosphorylation of SHC1 by p-EGFR mutants
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| comment |
has a Stoichiometric coefficient of 2
Edited: Wu, G, 2011-11-07
Authored: Orlic-Milacic, M, 2011-11-04
Edited: D'Eustachio, P, 2011-11-07
Edited: Matthews, L, 2011-11-07
Reviewed: Greulich, H, 2011-11-15
Reviewed: Savas, S, 2011-11-15
Constitutive phosphorylation of SHC1 was directly demonstrated in cells expressing EGFR L858R mutant (Greulich et al. 2005). Other EGFR cancer mutants were not directly tested for their ability to phosphorylate SHC1, but are assumed to interact with SHC1 in the same way as the wild-type EGFR protein.
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| prefLabel |
Phosphorylation of SHC1 by p-EGFR mutants
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| definition source |
Reactome, http://www.reactome.org
Pubmed16187797
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| prefixIRI |
HINO:0009759
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| seeAlso |
ReactomeREACT_115841
EC Number: 2.7.10
Reactome Database ID Release 431225952
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| subClassOf | |
| type | |
| has input | |
| has output |
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