Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

HSP90 is inactivated by binding to benzaquinoid ansamycins
Synonyms
Definitions

has a Stoichiometric coefficient of 2 Edited: Wu, G, 2011-11-07 Edited: Jassal, B, 2011-11-07 Authored: Orlic-Milacic, M, 2011-11-04 Edited: D'Eustachio, P, 2011-11-07 Benzoquinoid ansamycins (geldanamycin, herbimycin, and geldanamycin derivatives 17-AAG, 17-DMAG and IPI-504) are antitumor antibiotics that inactivate HSP90 by binding to its substrate-binding pocket. Edited: Matthews, L, 2011-11-07 Reviewed: Greulich, H, 2011-11-15 Reviewed: Savas, S, 2011-11-15

ID

http://purl.obolibrary.org/obo/HINO_0009692

comment

has a Stoichiometric coefficient of 2

Edited: Wu, G, 2011-11-07

Edited: Jassal, B, 2011-11-07

Authored: Orlic-Milacic, M, 2011-11-04

Edited: D'Eustachio, P, 2011-11-07

Benzoquinoid ansamycins (geldanamycin, herbimycin, and geldanamycin derivatives 17-AAG, 17-DMAG and IPI-504) are antitumor antibiotics that inactivate HSP90 by binding to its substrate-binding pocket.

Edited: Matthews, L, 2011-11-07

Reviewed: Greulich, H, 2011-11-15

Reviewed: Savas, S, 2011-11-15

definition source

Pubmed9108479

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/HINO_0012483

http://purl.obolibrary.org/obo/HINO_0004969

has output

http://purl.obolibrary.org/obo/HINO_0012490

label

HSP90 is inactivated by binding to benzaquinoid ansamycins

prefixIRI

HINO:0009692

prefLabel

HSP90 is inactivated by binding to benzaquinoid ansamycins

seeAlso

ReactomeREACT_115865

Reactome Database ID Release 431218824

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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