Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Activated RAF1 complex binds MEK

Synonyms
Definitions

Edited: Schmidt, EE, 0000-00-00 00:00:00 MEK-1/2 have a proline rich domain (P) and critical Serine residues (MEK-1 S218/222, MEK-2 unknown, S) upon which the molecules may be phosphorylated. MEK1/2 are found in the cytoplasm of unstimulated cells.<br>MEK-1/2 bind to active Raf-1 via the proline-rich domain. Active Raf-1 is able to phosphorylate target Serine and Threonine residues in the presence of ATP. Authored: Charalambous, M, 2005-01-07 11:17:43

ID

http://purl.obolibrary.org/obo/HINO_0009582

comment

Edited: Schmidt, EE, 0000-00-00 00:00:00

MEK-1/2 have a proline rich domain (P) and critical Serine residues (MEK-1 S218/222, MEK-2 unknown, S) upon which the molecules may be phosphorylated. MEK1/2 are found in the cytoplasm of unstimulated cells.
MEK-1/2 bind to active Raf-1 via the proline-rich domain. Active Raf-1 is able to phosphorylate target Serine and Threonine residues in the presence of ATP.

Authored: Charalambous, M, 2005-01-07 11:17:43

definition source

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/HINO_0025201

http://purl.obolibrary.org/obo/HINO_0011953

has output

http://purl.obolibrary.org/obo/HINO_0011930

label

Activated RAF1 complex binds MEK

prefixIRI

HINO:0009582

prefLabel

Activated RAF1 complex binds MEK

seeAlso

Reactome Database ID Release 43109830

ReactomeREACT_143

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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