loading...| Preferred Name |
Phosphorylated human RAF1 binds to RAS:GTP complex |
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| Synonyms |
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| Definitions |
A key event for Ras transformation involves the direct physical association between Ras and the Raf-1 kinase. This interaction promotes both Raf translocation to the plasma membrane and activation of Raf kinase activity. Reviewed: Dooms, H, 2011-03-17 Reviewed: Villarino, A, 2011-02-11 Edited: Jupe, S, 2010-08-06 Authored: Williams, MG, 2007-10-30 11:44:05 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0009581 |
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| comment |
A key event for Ras transformation involves the direct physical association between Ras and the Raf-1 kinase. This interaction promotes both Raf translocation to the plasma membrane and activation of Raf kinase activity. Reviewed: Dooms, H, 2011-03-17 Reviewed: Villarino, A, 2011-02-11 Edited: Jupe, S, 2010-08-06 Authored: Williams, MG, 2007-10-30 11:44:05 |
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| definition source |
Pubmed7811320 Reactome, http://www.reactome.org Pubmed7730360 |
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| label |
Phosphorylated human RAF1 binds to RAS:GTP complex |
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| prefixIRI |
HINO:0009581 |
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| prefLabel |
Phosphorylated human RAF1 binds to RAS:GTP complex |
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| seeAlso |
Reactome Database ID Release 43209207 ReactomeREACT_23877 |
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