loading...| Preferred Name |
Stabilisation of RAS:RAF by 14-3-3 |
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Edited: Schmidt, EE, 0000-00-00 00:00:00 14-3-3 has been displaced from Ser259. 14-3-3 may now bind its higher affinity Ser621 (S2) site. This stabilises an 'open' Raf-1 conformation that is catalytically active, and bound to p21ras via both p21ras-binding domains, CRD and RBD. Authored: Charalambous, M, 2005-01-07 11:17:43 |
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http://purl.obolibrary.org/obo/HINO_0009579 |
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Edited: Schmidt, EE, 0000-00-00 00:00:00 14-3-3 has been displaced from Ser259. 14-3-3 may now bind its higher affinity Ser621 (S2) site. This stabilises an 'open' Raf-1 conformation that is catalytically active, and bound to p21ras via both p21ras-binding domains, CRD and RBD. Authored: Charalambous, M, 2005-01-07 11:17:43 |
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| definition source |
Reactome, http://www.reactome.org Pubmed9069260 |
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Stabilisation of RAS:RAF by 14-3-3 |
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HINO:0009579 |
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Stabilisation of RAS:RAF by 14-3-3 |
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ReactomeREACT_996 Reactome Database ID Release 43109802 |
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