Preferred Name | Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 | |
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Edited: Orlic-Milacic, Marija, 2011-08-25 Reviewed: Heldin, CH, 2008-02-12 09:44:02 The Src homology 2 (SH2) domain of the phosphatidylinositol 3-kinase (PIK3) regulatory subunit (PIK3R1, i.e. PI3Kp85) binds to GAB1 in a phosphorylation-independent manner. GAB1 serves as a docking protein which recruits a number of downstream signalling proteins. PIK3R1 can bind to either GAB1 or phosphorylated GAB1. Authored: Castagnoli, L, 2006-10-10 13:09:34 |
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http://purl.obolibrary.org/obo/HINO_0009539 |
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comment |
Edited: Orlic-Milacic, Marija, 2011-08-25 Reviewed: Heldin, CH, 2008-02-12 09:44:02 The Src homology 2 (SH2) domain of the phosphatidylinositol 3-kinase (PIK3) regulatory subunit (PIK3R1, i.e. PI3Kp85) binds to GAB1 in a phosphorylation-independent manner. GAB1 serves as a docking protein which recruits a number of downstream signalling proteins. PIK3R1 can bind to either GAB1 or phosphorylated GAB1. Authored: Castagnoli, L, 2006-10-10 13:09:34 |
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definition source |
Reactome, http://www.reactome.org Pubmed11606067 |
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label |
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 |
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prefixIRI |
HINO:0009539 |
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prefLabel |
Binding of PIK3 regulatory alpha subunit to GRB2:GAB1 |
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seeAlso |
ReactomeREACT_12616 Reactome Database ID Release 43177931 |
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