Preferred Name | GRB2:GAB1:PIK3R1 binds to phosphorylated EGFR | |
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Definitions |
Edited: Orlic-Milacic, Marija, 2011-08-25 Reviewed: Heldin, CH, 2008-02-12 09:44:02 The regulatory subunit of PIK3 mediates the association of GAB1 and receptor protein-tyrosine kinases such as the EGF receptor, which can phosphorylate GAB1. It appears that the PIK3 regulatory subunit acts as an adaptor protein allowing GAB1 to serve as a substrate for several tyrosine kinases. Authored: Castagnoli, L, 2006-10-10 13:09:34 |
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ID |
http://purl.obolibrary.org/obo/HINO_0009537 |
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comment |
Edited: Orlic-Milacic, Marija, 2011-08-25 Reviewed: Heldin, CH, 2008-02-12 09:44:02 The regulatory subunit of PIK3 mediates the association of GAB1 and receptor protein-tyrosine kinases such as the EGF receptor, which can phosphorylate GAB1. It appears that the PIK3 regulatory subunit acts as an adaptor protein allowing GAB1 to serve as a substrate for several tyrosine kinases. Authored: Castagnoli, L, 2006-10-10 13:09:34 |
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definition source |
Pubmed9356464 Reactome, http://www.reactome.org |
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label |
GRB2:GAB1:PIK3R1 binds to phosphorylated EGFR |
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prefixIRI |
HINO:0009537 |
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prefLabel |
GRB2:GAB1:PIK3R1 binds to phosphorylated EGFR |
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seeAlso |
Reactome Database ID Release 43177941 ReactomeREACT_12425 |
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subClassOf |