loading...| Preferred Name | PIP3 recruits PDPK1 to the membrane | |
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| Definitions |
Reviewed: Yuzugullu, Haluk, 2012-08-13 Edited: Matthews, L, 2012-08-03 Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 Reviewed: Greene, LA, 2007-11-08 15:39:37 Reviewed: Zhao, Jean J, 2012-08-13 Reviewed: Thorpe, Lauren, 2012-08-13 PIP3 generated by PI3K recruits phosphatidylinositide-dependent protein kinase 1 (PDPK1 i.e. PDK1) to the membrane, through its PH (pleckstrin-homology) domain. PDPK1 binds PIP3 with high affinity, and also shows low affinity for PIP2 (Currie et al. 1999). |
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| ID |
http://purl.obolibrary.org/obo/HINO_0009518 |
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| comment |
Reviewed: Yuzugullu, Haluk, 2012-08-13 Edited: Matthews, L, 2012-08-03 Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 Reviewed: Greene, LA, 2007-11-08 15:39:37 Reviewed: Zhao, Jean J, 2012-08-13 Reviewed: Thorpe, Lauren, 2012-08-13 PIP3 generated by PI3K recruits phosphatidylinositide-dependent protein kinase 1 (PDPK1 i.e. PDK1) to the membrane, through its PH (pleckstrin-homology) domain. PDPK1 binds PIP3 with high affinity, and also shows low affinity for PIP2 (Currie et al. 1999). |
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| definition source |
Reactome, http://www.reactome.org Pubmed9895304 |
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| label |
PIP3 recruits PDPK1 to the membrane |
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| prefixIRI |
HINO:0009518 |
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| prefLabel |
PIP3 recruits PDPK1 to the membrane |
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| seeAlso |
Reactome Database ID Release 432316429 ReactomeREACT_147873 |
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