Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Sustained activation of SRC kinase by SHP2
Synonyms
Definitions

Reviewed: Heldin, CH, 2008-02-12 09:44:02 SHP2 can dephosphorylate paxillin, which leads to Csk dissociation from the paxillin-Src complex and Src activation. Src is an SHP2 effector in EGF-stimulated Erk activation and cell migration. Authored: Castagnoli, L, 2006-10-10 13:09:34

ID

http://purl.obolibrary.org/obo/HINO_0009512

comment

Reviewed: Heldin, CH, 2008-02-12 09:44:02

SHP2 can dephosphorylate paxillin, which leads to Csk dissociation from the paxillin-Src complex and Src activation. Src is an SHP2 effector in EGF-stimulated Erk activation and cell migration.

Authored: Castagnoli, L, 2006-10-10 13:09:34

definition source

Reactome, http://www.reactome.org

Pubmed15574420

has input

http://purl.obolibrary.org/obo/HINO_0012574

http://purl.obolibrary.org/obo/CHEBI_15377

has output

http://purl.obolibrary.org/obo/HINO_0012573

http://purl.obolibrary.org/obo/UniProt_P41240

http://purl.obolibrary.org/obo/CHEBI_18367

label

Sustained activation of SRC kinase by SHP2

prefixIRI

HINO:0009512

prefLabel

Sustained activation of SRC kinase by SHP2

seeAlso

Reactome Database ID Release 43177923

ReactomeREACT_12601

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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