loading...| Preferred Name | Activation of SHP2 through the binding to phospho-Gab1 | |
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Reviewed: Heldin, CH, 2008-02-12 09:44:02 The SH2 domains repress phosphatase activity of SHP2. Binding of these domains to phosphotyrosine-containing proteins relieves this autoinhibition, possibly by inducing a conformational change in the enzyme. Authored: Castagnoli, L, 2006-10-10 13:09:34 |
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http://purl.obolibrary.org/obo/HINO_0009508 |
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Reviewed: Heldin, CH, 2008-02-12 09:44:02 The SH2 domains repress phosphatase activity of SHP2. Binding of these domains to phosphotyrosine-containing proteins relieves this autoinhibition, possibly by inducing a conformational change in the enzyme. Authored: Castagnoli, L, 2006-10-10 13:09:34 |
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| definition source |
Reactome, http://www.reactome.org Pubmed14701753 Pubmed11323411 |
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Activation of SHP2 through the binding to phospho-Gab1 |
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HINO:0009508 |
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Activation of SHP2 through the binding to phospho-Gab1 |
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ReactomeREACT_12466 Reactome Database ID Release 43177944 |
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