loading...| Preferred Name | Gab1 binds phosphatidylinositol-3,4,5-trisphosphate | |
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| Definitions |
Edited: Orlic-Milacic, Marija, 2011-08-25 Reviewed: Heldin, CH, 2008-02-12 09:44:02 The pleckstrin homology (PH) domain of GAB1 binds to PIP3 and can target GAB1 to the plasma membrane in response to EGF stimulation. This mechanism provides a positive feedback loop with respect to PI3K activation, to enhance EGFR signalling. Authored: Castagnoli, L, 2006-10-10 13:09:34 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0009507 |
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Edited: Orlic-Milacic, Marija, 2011-08-25 Reviewed: Heldin, CH, 2008-02-12 09:44:02 The pleckstrin homology (PH) domain of GAB1 binds to PIP3 and can target GAB1 to the plasma membrane in response to EGF stimulation. This mechanism provides a positive feedback loop with respect to PI3K activation, to enhance EGFR signalling. Authored: Castagnoli, L, 2006-10-10 13:09:34 |
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| definition source |
Reactome, http://www.reactome.org Pubmed10648629 |
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Gab1 binds phosphatidylinositol-3,4,5-trisphosphate |
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| prefixIRI |
HINO:0009507 |
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| prefLabel |
Gab1 binds phosphatidylinositol-3,4,5-trisphosphate |
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| seeAlso |
ReactomeREACT_12534 Reactome Database ID Release 43179467 |
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