Preferred Name | THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation | |
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Definitions |
Reviewed: Yuzugullu, Haluk, 2012-08-13 Edited: Matthews, L, 2012-08-03 Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 Reviewed: Greene, LA, 2007-11-08 15:39:37 The phosphorylation of membrane-recruited AKT at threonine and serine can be inhibited by direct binding of two different proteins, C-terminal modulator protein (THEM4 i.e. CTMP), which binds to the carboxy-terminal tail of AKT (Maira et al. 2001), or Tribbles homolog 3 (TRIB3), which binds to the catalytic domain of AKT (Du et al. 2003). Reviewed: Zhao, Jean J, 2012-08-13 Reviewed: Thorpe, Lauren, 2012-08-13 |
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ID |
http://purl.obolibrary.org/obo/HINO_0009493 |
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comment |
Reviewed: Yuzugullu, Haluk, 2012-08-13 Edited: Matthews, L, 2012-08-03 Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 Reviewed: Greene, LA, 2007-11-08 15:39:37 The phosphorylation of membrane-recruited AKT at threonine and serine can be inhibited by direct binding of two different proteins, C-terminal modulator protein (THEM4 i.e. CTMP), which binds to the carboxy-terminal tail of AKT (Maira et al. 2001), or Tribbles homolog 3 (TRIB3), which binds to the catalytic domain of AKT (Du et al. 2003). Reviewed: Zhao, Jean J, 2012-08-13 Reviewed: Thorpe, Lauren, 2012-08-13 |
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definition source |
Reactome, http://www.reactome.org Pubmed11598301 Pubmed12791994 |
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label |
THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation |
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prefixIRI |
HINO:0009493 |
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prefLabel |
THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation |
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seeAlso |
ReactomeREACT_12567 Reactome Database ID Release 43199443 |
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subClassOf |