Link to this page
Human Interaction Network Ontology
Last uploaded:
June 27, 2014
Jump to:
| Id | http://purl.obolibrary.org/obo/HINO_0009493
http://purl.obolibrary.org/obo/HINO_0009493
|
|---|---|
| Preferred Name | THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation |
| Definitions |
Reviewed: Yuzugullu, Haluk, 2012-08-13
Edited: Matthews, L, 2012-08-03
Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07
Reviewed: Greene, LA, 2007-11-08 15:39:37
The phosphorylation of membrane-recruited AKT at threonine and serine can be inhibited by direct binding of two different proteins, C-terminal modulator protein (THEM4 i.e. CTMP), which binds to the carboxy-terminal tail of AKT (Maira et al. 2001), or Tribbles homolog 3 (TRIB3), which binds to the catalytic domain of AKT (Du et al. 2003).
Reviewed: Zhao, Jean J, 2012-08-13
Reviewed: Thorpe, Lauren, 2012-08-13
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| label | THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation
|
|---|---|
| comment | Reviewed: Yuzugullu, Haluk, 2012-08-13
Edited: Matthews, L, 2012-08-03
Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07
Reviewed: Greene, LA, 2007-11-08 15:39:37
The phosphorylation of membrane-recruited AKT at threonine and serine can be inhibited by direct binding of two different proteins, C-terminal modulator protein (THEM4 i.e. CTMP), which binds to the carboxy-terminal tail of AKT (Maira et al. 2001), or Tribbles homolog 3 (TRIB3), which binds to the catalytic domain of AKT (Du et al. 2003).
Reviewed: Zhao, Jean J, 2012-08-13
Reviewed: Thorpe, Lauren, 2012-08-13
See more
See less
|
| prefLabel | THEM4 (CTMP) and/or TRIB3 inhibit AKT phosphorylation
|
| definition source |
Reactome, http://www.reactome.org
Pubmed11598301
Pubmed12791994
|
| prefixIRI | HINO:0009493
|
| seeAlso |
ReactomeREACT_12567
Reactome Database ID Release 43199443
|
| subClassOf | |
| type | |
| has input | |
| has output |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |