loading...| Preferred Name | AKT can phosphorylate NR4A1 (NUR77) | |
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| Definitions |
AKT inhibits DNA binding of NUR77 and inhibits its pro-apoptotic function (PMID 11438550). However, the relevance of AKT for NUR77 phosphorylation has recently been questioned: according to recent work, NUR77 is phosphorylated by RSK (and MSK) rather than by AKT (PMID 16223362). Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 Reviewed: Greene, LA, 2007-11-08 15:39:37 |
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http://purl.obolibrary.org/obo/HINO_0009485 |
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| comment |
AKT inhibits DNA binding of NUR77 and inhibits its pro-apoptotic function (PMID 11438550). However, the relevance of AKT for NUR77 phosphorylation has recently been questioned: according to recent work, NUR77 is phosphorylated by RSK (and MSK) rather than by AKT (PMID 16223362). Authored: Nasi, S, Annibali, D, 2006-10-10 09:07:07 Reviewed: Greene, LA, 2007-11-08 15:39:37 |
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| definition source |
Reactome, http://www.reactome.org Pubmed11274386 |
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AKT can phosphorylate NR4A1 (NUR77) |
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| prefixIRI |
HINO:0009485 |
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AKT can phosphorylate NR4A1 (NUR77) |
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| seeAlso |
ReactomeREACT_12614 Reactome Database ID Release 43199863 EC Number: 2.7.11 |
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