loading...| Preferred Name | Viral dsRNA:TLR3 recruits TRIF | |
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| Definitions |
has a Stoichiometric coefficient of 2 Reviewed: Fitzgerald, Katherine A, 2012-11-13 Authored: Luo, F, 2005-11-10 11:23:18 Edited: Shamovsky, V, 2009-12-16 Reviewed: Gay, NJ, 2006-04-24 16:48:17 TIR-domain-containing adaptor inducing interferon-beta (TRIF or TICAM1) was shown to play an essential role in TLR3 signaling. All poly(I:C)-induced pathways leading to NFkB and IRF3 activation were abolished in TRIF-/- mice [Yamamoto et al. 2003]. |
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| ID |
http://purl.obolibrary.org/obo/HINO_0009332 |
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| comment |
has a Stoichiometric coefficient of 2 Reviewed: Fitzgerald, Katherine A, 2012-11-13 Authored: Luo, F, 2005-11-10 11:23:18 Edited: Shamovsky, V, 2009-12-16 Reviewed: Gay, NJ, 2006-04-24 16:48:17 TIR-domain-containing adaptor inducing interferon-beta (TRIF or TICAM1) was shown to play an essential role in TLR3 signaling. All poly(I:C)-induced pathways leading to NFkB and IRF3 activation were abolished in TRIF-/- mice [Yamamoto et al. 2003]. |
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| definition source |
Reactome, http://www.reactome.org Pubmed14517278 Pubmed12855817 Pubmed12539043 |
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| label |
Viral dsRNA:TLR3 recruits TRIF |
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| prefixIRI |
HINO:0009332 |
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| prefLabel |
Viral dsRNA:TLR3 recruits TRIF |
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| seeAlso |
Reactome Database ID Release 43168929 ReactomeREACT_6919 |
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