Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Viral dsRNA binds the Toll-Like Receptor 3 (TLR3)
Synonyms
Definitions

has a Stoichiometric coefficient of 2 Authored: Luo, F, 2005-11-10 11:23:18 Reviewed: Gay, NJ, 2006-04-24 16:48:17 Edited: Shamovsky, V, 2012-02-19 Viral dsRNA triggers an antiviral pathway mediated by toll like receptor 3. TLR3 dimerization occurs upon ligand binding to positivly charged residues on the ectodomain termini of TLR3 wich are responsible for the interaction with sugar-phosphate groups of dsRNA.

ID

http://purl.obolibrary.org/obo/HINO_0009330

comment

has a Stoichiometric coefficient of 2

Authored: Luo, F, 2005-11-10 11:23:18

Reviewed: Gay, NJ, 2006-04-24 16:48:17

Edited: Shamovsky, V, 2012-02-19

Viral dsRNA triggers an antiviral pathway mediated by toll like receptor 3. TLR3 dimerization occurs upon ligand binding to positivly charged residues on the ectodomain termini of TLR3 wich are responsible for the interaction with sugar-phosphate groups of dsRNA.

definition source

Pubmed18420935

Pubmed11607032

Reactome, http://www.reactome.org

has input

http://purl.obolibrary.org/obo/UniProt_O15455

http://purl.obolibrary.org/obo/HINO_0005700

has output

http://purl.obolibrary.org/obo/HINO_0005128

label

Viral dsRNA binds the Toll-Like Receptor 3 (TLR3)

prefixIRI

HINO:0009330

prefLabel

Viral dsRNA binds the Toll-Like Receptor 3 (TLR3)

seeAlso

ReactomeREACT_6753

Reactome Database ID Release 43168092

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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