Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

Association of LBP with LPS
Synonyms
Definitions

Authored: de Bono, B, 2005-08-16 10:54:15 Reviewed: Gay, NJ, 2006-04-24 16:48:17 Lipopolysaccharide-binding protein (LBP) is a ~60-kDa serum glycoprotein which transfers LPS to both membrane-bound and soluble CD14. The LPS binding site of LBP consists of basic residues that bind the phosphorylated head of the bacterial lipid A. <p>LBP is an acute-phase opsonin that binds gram-negative bacteria and bacterial fragments and promote the interaction of coated bacteria with phagocytes. Reviewed: Granucci, Francesca, Zanoni, Ivan, 2012-11-13 Reviewed: Gillespie, ME, 2010-11-30 Edited: Shamovsky, V, 2010-11-16

ID

http://purl.obolibrary.org/obo/HINO_0009157

comment

Authored: de Bono, B, 2005-08-16 10:54:15

Reviewed: Gay, NJ, 2006-04-24 16:48:17

Lipopolysaccharide-binding protein (LBP) is a ~60-kDa serum glycoprotein which transfers LPS to both membrane-bound and soluble CD14. The LPS binding site of LBP consists of basic residues that bind the phosphorylated head of the bacterial lipid A.

LBP is an acute-phase opsonin that binds gram-negative bacteria and bacterial fragments and promote the interaction of coated bacteria with phagocytes.

Reviewed: Granucci, Francesca, Zanoni, Ivan, 2012-11-13

Reviewed: Gillespie, ME, 2010-11-30

Edited: Shamovsky, V, 2010-11-16

definition source

Pubmed19269309

Reactome, http://www.reactome.org

Pubmed2477488

Pubmed1698311

has input

http://purl.obolibrary.org/obo/UniProt_P18428

http://purl.obolibrary.org/obo/CHEBI_16412

has output

http://purl.obolibrary.org/obo/HINO_0005905

label

Association of LBP with LPS

prefixIRI

HINO:0009157

prefLabel

Association of LBP with LPS

seeAlso

Reactome Database ID Release 43166015

ReactomeREACT_6834

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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