Preferred Name | Association of LBP with LPS | |
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Definitions |
Authored: de Bono, B, 2005-08-16 10:54:15 Reviewed: Gay, NJ, 2006-04-24 16:48:17 Lipopolysaccharide-binding protein (LBP) is a ~60-kDa serum glycoprotein which transfers LPS to both membrane-bound and soluble CD14. The LPS binding site of LBP consists of basic residues that bind the phosphorylated head of the bacterial lipid A. <p>LBP is an acute-phase opsonin that binds gram-negative bacteria and bacterial fragments and promote the interaction of coated bacteria with phagocytes. Reviewed: Granucci, Francesca, Zanoni, Ivan, 2012-11-13 Reviewed: Gillespie, ME, 2010-11-30 Edited: Shamovsky, V, 2010-11-16 |
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ID |
http://purl.obolibrary.org/obo/HINO_0009157 |
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comment |
Authored: de Bono, B, 2005-08-16 10:54:15 Reviewed: Gay, NJ, 2006-04-24 16:48:17 Lipopolysaccharide-binding protein (LBP) is a ~60-kDa serum glycoprotein which transfers LPS to both membrane-bound and soluble CD14. The LPS binding site of LBP consists of basic residues that bind the phosphorylated head of the bacterial lipid A. LBP is an acute-phase opsonin that binds gram-negative bacteria and bacterial fragments and promote the interaction of coated bacteria with phagocytes. Reviewed: Granucci, Francesca, Zanoni, Ivan, 2012-11-13 Reviewed: Gillespie, ME, 2010-11-30 Edited: Shamovsky, V, 2010-11-16 |
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definition source |
Pubmed19269309 Reactome, http://www.reactome.org Pubmed2477488 Pubmed1698311 |
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label |
Association of LBP with LPS |
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prefixIRI |
HINO:0009157 |
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prefLabel |
Association of LBP with LPS |
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seeAlso |
Reactome Database ID Release 43166015 ReactomeREACT_6834 |
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subClassOf |