Human Interaction Network Ontology

Last uploaded: June 27, 2014
Preferred Name

MyD88 forms a complex with MAL:activated TLR2/4
Synonyms
Definitions

has a Stoichiometric coefficient of 2 Authored: de Bono, B, 2005-08-16 10:54:15 Reviewed: Gay, NJ, 2006-04-24 16:48:17 MyD88 binds to IRAK (IL-1 receptor-associated kinase) and the receptor heterocomplex (the signaling complex) and thereby mediates the association of IRAK with the receptor. MyD88 therefore couples a serine/threonine protein kinase to the receptor complex. Reviewed: Napetschnig, Johanna, 2012-11-16 Edited: Shamovsky, V, 2012-11-06 Reviewed: Gillespie, ME, 2010-11-30

ID

http://purl.obolibrary.org/obo/HINO_0009140

comment

has a Stoichiometric coefficient of 2

Authored: de Bono, B, 2005-08-16 10:54:15

Reviewed: Gay, NJ, 2006-04-24 16:48:17

MyD88 binds to IRAK (IL-1 receptor-associated kinase) and the receptor heterocomplex (the signaling complex) and thereby mediates the association of IRAK with the receptor. MyD88 therefore couples a serine/threonine protein kinase to the receptor complex.

Reviewed: Napetschnig, Johanna, 2012-11-16

Edited: Shamovsky, V, 2012-11-06

Reviewed: Gillespie, ME, 2010-11-30

definition source

Reactome, http://www.reactome.org

Pubmed9430229

Pubmed12447441

Pubmed12447442

has input

http://purl.obolibrary.org/obo/UniProt_Q99836

http://purl.obolibrary.org/obo/HINO_0006009

has output

http://purl.obolibrary.org/obo/HINO_0005999

label

MyD88 forms a complex with MAL:activated TLR2/4

prefixIRI

HINO:0009140

prefLabel

MyD88 forms a complex with MAL:activated TLR2/4

seeAlso

Reactome Database ID Release 43166072

ReactomeREACT_6797

subClassOf

http://purl.obolibrary.org/obo/INO_0000040

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