Link to this page
Human Interaction Network Ontology
Last uploaded:
June 27, 2014
Jump to:
| Preferred Name | Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:Mal:p-IRAK4 complex | |
| Synonyms |
|
|
| Definitions |
Authored: de Bono, B, 2005-08-16 10:54:15 has a Stoichiometric coefficient of 4 Reviewed: Napetschnig, Johanna, 2012-11-16 Edited: Shamovsky, V, 2012-11-06 Reviewed: Gillespie, ME, 2010-11-30 Hyperphosphorylated IRAK1 and TRAF6 are thought to dissociate from the activated receptor. (Gottipati et al. 2007) but the IRAK1:TRAF6 complex may remain associated with the membrane (Dong et al. 2006).<p> Phosphorylated IRAK2, like its paralog IRAK1, possibly dissociates from the activated receptor as shown here, although mechanism of IRAK2 activation by IRAK4 followed by TRAF6 binding remains to be deciphered. |
|
| ID |
http://purl.obolibrary.org/obo/HINO_0009132 |
|
| comment |
Authored: de Bono, B, 2005-08-16 10:54:15 has a Stoichiometric coefficient of 4 Reviewed: Napetschnig, Johanna, 2012-11-16 Edited: Shamovsky, V, 2012-11-06 Reviewed: Gillespie, ME, 2010-11-30 Hyperphosphorylated IRAK1 and TRAF6 are thought to dissociate from the activated receptor. (Gottipati et al. 2007) but the IRAK1:TRAF6 complex may remain associated with the membrane (Dong et al. 2006).<p> Phosphorylated IRAK2, like its paralog IRAK1, possibly dissociates from the activated receptor as shown here, although mechanism of IRAK2 activation by IRAK4 followed by TRAF6 binding remains to be deciphered.
|
|
| definition source |
Pubmed16831874 Pubmed17890055 Reactome, http://www.reactome.org Pubmed14625308
|
|
| has input | ||
| has output | ||
| label |
Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:Mal:p-IRAK4 complex
|
|
| prefixIRI |
HINO:0009132
|
|
| prefLabel |
Dissociation of p-IRAK2:TRAF6 from the activated TLR:oligo-Myd88:Mal:p-IRAK4 complex
|
|
| seeAlso |
Reactome Database ID Release 432262775 ReactomeREACT_121298
|
|
| subClassOf |
Add comment
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |