loading...| Preferred Name | TRAF6 binds to p-IRAK2 | |
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| Definitions |
IRAK-2 has two TRAF6 binding motifs that are responsible for initiating TRAF6 signaling transduction (Ye H et al 2002). IRAK2 point mutants with mutated TRAF6-binding motifs abrogate NFkB activation and are incapable to stimulate TRAF6 ubiquitination (Keating SE et al 2007). has a Stoichiometric coefficient of 4 Reviewed: Napetschnig, Johanna, 2012-11-16 Authored: Shamovsky, V, 2012-04-19 Edited: Shamovsky, V, 2012-11-06 Reviewed: Gillespie, ME, 2010-11-30 |
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| ID |
http://purl.obolibrary.org/obo/HINO_0009130 |
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| comment |
IRAK-2 has two TRAF6 binding motifs that are responsible for initiating TRAF6 signaling transduction (Ye H et al 2002). IRAK2 point mutants with mutated TRAF6-binding motifs abrogate NFkB activation and are incapable to stimulate TRAF6 ubiquitination (Keating SE et al 2007). has a Stoichiometric coefficient of 4 Reviewed: Napetschnig, Johanna, 2012-11-16 Authored: Shamovsky, V, 2012-04-19 Edited: Shamovsky, V, 2012-11-06 Reviewed: Gillespie, ME, 2010-11-30 |
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| definition source |
Pubmed8837778 Pubmed12140561 Pubmed18070982 Reactome, http://www.reactome.org Pubmed12138165 Pubmed17878161 |
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| label |
TRAF6 binds to p-IRAK2 |
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| prefixIRI |
HINO:0009130 |
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| prefLabel |
TRAF6 binds to p-IRAK2 |
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| seeAlso |
ReactomeREACT_120733 Reactome Database ID Release 432262777 |
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